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Researching Emotions And Cardiac Health (REACH): Phase III

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Conditions:   Congestive Heart Failure;   Emotions;   Patient Compliance
Interventions:   Behavioral: PP-based health behavior intervention;   Behavioral: MI-based educational control condition
Sponsors:   Massachusetts General Hospital;   National Institutes of Health (NIH);   National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting - verified July 2017

Pink and White Esthetic Scores of Polymer-infiltrated-ceramic-network and Lithium Disilicate Implant Hybrid Abutment Crowns

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Condition:   Dental Implants
Interventions:   Other: PICN (VITA Enamic) hybrid abutment crown;   Other: Lithium disilicate (IPS e.max) hybrid abutment crown
Sponsor:   Cairo University
Not yet recruiting - verified July 2017

SBRT + PD-1/PDL-1 Inhibiting Therapy for Advanced Solid Tumors After Progression on PD-1/PDL-1 Tx

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Condition:   Solid Tumor
Interventions:   Radiation: Stereotactic radiotherapy;   Other: Biological: humanized anti-PD-1 monoclonal antibody;   Other: Biological: humanized anti-PD-L1 monoclonal antibody
Sponsors:   Virginia Commonwealth University;   National Cancer Institute (NCI)
Not yet recruiting - verified July 2017

Stem Cell Coated Fistula Plug in Patients With Crohn's RVF

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Conditions:   Fistula Vagina;   Crohn Disease
Intervention:   Drug: MSC-AFP
Sponsor:   Mayo Clinic
Not yet recruiting - verified July 2017

Imaging GABAergic/Glutamatergic Drugs in Bipolar Alcoholics Alcoholics

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Conditions:   Alcohol Use Disorder;   Bipolar Disorder
Interventions:   Drug: N-Acetylcysteine;   Drug: Gabapentin;   Drug: Placebo Oral Tablet
Sponsors:   Medical University of South Carolina;   National Institutes of Health (NIH);   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified July 2017

Low Speed Drilling Versus Conventional Drilling Technique on Crestal Bone Level in Maxilla.(Group C ) A Randomized Controlled Clinical Trial

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Condition:   Bone Resorption
Interventions:   Procedure: Drilling at low speed;   Procedure: Drilling at conventional or high speed
Sponsor:   Cairo University
Active, not recruiting - verified July 2017

Low Speed Drilling Versus Conventional Drilling Technique on Crestal Bone Level in Maxilla.(Group A ) A Randomized Controlled Clinical Trial

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Condition:   Bone Resorption
Interventions:   Procedure: Drilling at low speed;   Procedure: Conventional drilling at high speed
Sponsor:   Cairo University
Active, not recruiting - verified July 2017

The Application of Music Therapy in Female Amphetamine Use Disorder

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Condition:   Amphetamine Addiction
Intervention:   Behavioral: Music therapy group
Sponsor:   Shanghai Mental Health Center
Not yet recruiting - verified July 2017

Comparison of Molecular Breast Imaging and Digital Breast Tomosynthesis for Screening in Women With Dense Breasts

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Condition:   Breast Cancer
Interventions:   Diagnostic Test: Molecular Breast Imaging;   Diagnostic Test: Digital Breast Tomosynthesis
Sponsor:   Mayo Clinic
Recruiting - verified July 2017

Cognitive Functional Therapy for Chronic Low Back Pain

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Conditions:   Low Back Pain;   Back Pain;   Pain;   Signs and Symptoms;   Neuromuscular Manifestations
Interventions:   Behavioral: Cognitive Functional Therapy;   Other: Manual Therapy and Motor Control Exercise
Sponsors:   Centro Universitário Augusto Motta;   Rio de Janeiro State Research Supporting Foundation (FAPERJ)
Not yet recruiting - verified July 2017

MOTIVATIONAL INTERVIEWING IN TOBACCO GROUPS

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Conditions:   Smoking, Tobacco;   Smoking Cessation
Interventions:   Behavioral: Motivational Interviewing;   Behavioral: Traditional cognitive-behavioral approach
Sponsors:   Hospital Nossa Senhora da Conceicao;   Federal University of Rio Grande do Sul
Recruiting - verified July 2017

Maximum Biting Force of Inject Able Thermoplastic Resin Versus Conventional Resin in Complete Denture Patients

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Condition:   Biting Force
Interventions:   Device: thermoplastic complete denture;   Device: conventional acrylic resin complete denture
Sponsor:   Cairo University
Not yet recruiting - verified February 2017

Comparison of Patient-Controlled Analgesia With Different Background Infusion

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Condition:   Patient-Controlled Analgesia
Intervention:   Device: Patient-Controlled Analgesia(PCA)
Sponsor:   Weifeng Tu
Completed - verified July 2017

Early Intervention for Suicide Risk Among Immigrant Youth

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Conditions:   Family Conflict;   Suicidal Ideation
Interventions:   Behavioral: Early Intervention for Suicide Risk Among Immigrant Youth;   Behavioral: Enhanced usual care
Sponsor:   Massachusetts General Hospital
Not yet recruiting - verified July 2017

Clinical Analysis of HIPEC for T4 Colorectal Cancer After Surgery

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Condition:   Colorectal Neoplasms
Interventions:   Procedure: Surgery and HIPEC with Lobaplatin;   Procedure: Surgery without HIPEC
Sponsors:   Sixth Affiliated Hospital, Sun Yat-sen University;   Second Affiliated Hospital, Sun Yat-Sen University;   Zhujiang Hospital;   First Affiliated Hospital of Jinan University;   The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine;   Second Affiliated Hospital of Guangzhou Medical University;   Guangzhou General Hospital of Guangzhou Military Command;   Tcm-integrated Cancer Center of Southern Medical University;   Affiliated Tumor Hospital of Guangzhou Medical University;   Nanfang Hospital of Southern Medical University;   Guangdong Provincial Hospital of Traditional Chinese Medicine
Not yet recruiting - verified July 2017

Efficacy and Safety Study of Pembrolizumab (MK-3475) in Combination With Daratumumab in Participants With Relapsed Refractory Multiple Myeloma (MK-3475-668/KEYNOTE-668)

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Condition:   Multiple Myeloma
Interventions:   Biological: Pembrolizumab;   Biological: Daratumumab
Sponsor:   Merck Sharp & Dohme Corp.
Not yet recruiting - verified July 2017

Study of Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy in Participants With Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (MK-3475-585/KEYNOTE-585)

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Conditions:   Gastric Cancer;   Gastroesophageal Junction Cancer
Interventions:   Biological: Pembrolizumab;   Drug: Placebo;   Drug: Cisplatin;   Drug: Capecitabine;   Drug: 5-fluorouracil
Sponsor:   Merck Sharp & Dohme Corp.
Not yet recruiting - verified July 2017

Pediatric MATCH: Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With BRAF V600 Mutations

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Conditions:   Advanced Malignant Solid Neoplasm;   BRAF NP_004324.2:p.V600X;   Ependymoma;   Ewing Sarcoma;   Hepatoblastoma;   Histiocytosis;   Langerhans Cell Histiocytosis;   Malignant Germ Cell Tumor;   Malignant Glioma;   Osteosarcoma;   Peripheral Primitive Neuroectodermal Tumor;   Recurrent Childhood Central Nervous System Neoplasm;   Recurrent Childhood Non-Hodgkin Lymphoma;   Recurrent Malignant Solid Neoplasm;   Recurrent Neuroblastoma;   Refractory Central Nervous System Neoplasm;   Refractory Malignant Solid Neoplasm;   Refractory Neuroblastoma;   Refractory Non-Hodgkin Lymphoma;   Rhabdoid Tumor;   Rhabdomyosarcoma;   Soft Tissue Sarcoma;   Stage III Childhood Non-Hodgkin Lymphoma;   Stage IV Childhood Non-Hodgkin Lymphoma;   Wilms Tumor
Interventions:   Other: Laboratory Biomarker Analysis;   Drug: Vemurafenib
Sponsor:   National Cancer Institute (NCI)
Not yet recruiting - verified July 2017

Ibrutinib, Rituximab, Etoposide, Prednisone, Vincristine Sulfate, Cyclophosphamide, and Doxorubicin Hydrochloride in Treating Patients With HIV-Positive Stage II-IV Diffuse Large B-Cell Lymphomas

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Conditions:   AIDS-Related Lymphoma;   CD20 Positive;   HIV Positivity;   Stage II Diffuse Large B-Cell Lymphoma;   Stage III Diffuse Large B-Cell Lymphoma;   Stage IV Diffuse Large B-Cell Lymphoma
Interventions:   Drug: Cyclophosphamide;   Drug: Doxorubicin Hydrochloride;   Drug: Etoposide;   Biological: Filgrastim;   Drug: Ibrutinib;   Other: Laboratory Biomarker Analysis;   Biological: Pegfilgrastim;   Other: Pharmacological Study;   Drug: Prednisone;   Biological: Rituximab;   Drug: Vincristine Sulfate
Sponsor:   National Cancer Institute (NCI)
Not yet recruiting - verified July 2017

Nivolumab or Expectant Observation Following Ipilimumab, Nivolumab, and Surgery in Treating Patients With High Risk Localized, Locoregionally Advanced, or Recurrent Mucosal Melanoma

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Conditions:   Cervical Carcinoma;   Esophageal Carcinoma;   Mucosal Melanoma;   Mucosal Melanoma of the Head and Neck;   Oral Cavity Mucosal Melanoma;   Recurrent Melanoma;   Stage II Vulvar Cancer;   Stage III Vulvar Cancer;   Stage IIIA Vulvar Cancer;   Stage IIIB Vulvar Cancer;   Stage IIIC Vulvar Cancer;   Stage IV Oral Cavity Cancer AJCC v6 and v7;   Stage IV Vulvar Cancer;   Stage IVA Oral Cavity Cancer AJCC v6 and v7;   Stage IVB Oral Cavity Cancer AJCC v6 and v7;   Stage IVC Oral Cavity Cancer AJCC v6 and v7;   Vaginal Carcinoma
Interventions:   Procedure: Conventional Surgery;   Biological: Ipilimumab;   Other: Laboratory Biomarker Analysis;   Biological: Nivolumab;   Other: Patient Observation;   Radiation: Radiation Therapy
Sponsor:   National Cancer Institute (NCI)
Not yet recruiting - verified July 2017
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